Understanding Letrozole: An Overview

Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors. By inhibiting the aromatase enzyme, letrozole effectively lowers estrogen levels in the body, which can help slow the growth of certain types of breast tumors that require estrogen to grow.

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How Letrozole Works

Letrozole works by blocking the conversion of androgens to estrogens in the body. This reduction in estrogen levels is crucial for treating hormone receptor-positive breast cancer. The medication stops the cancer cells from receiving the hormones they need to grow and divide, leading to a decrease in tumor size and slowing the progression of the disease.

Uses of Letrozole

  1. Treatment of Breast Cancer: Primarily prescribed for postmenopausal women with early-stage or advanced breast cancer.
  2. Off-label Uses: Some doctors prescribe letrozole for conditions like infertility in women who have ovulatory disorders.

Potential Side Effects

As with any medication, letrozole can cause side effects. Common side effects include:

Conclusion

Letrozole has proven to be an effective treatment option for many women with hormone receptor-positive breast cancer. Always consult with a healthcare provider to determine if letrozole is the right choice for your specific health situation.